Use of X-Ray Crystallography in the Design of Antiviral Agents

Use of X-Ray Crystallography in the Design of Antiviral Agents

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Use of X-Ray Crystallography in the Design of Antiviral Agents describes materials presented at an International Workshop held in Kona, Hawaii on February 6-8, 1989, which discussed the use of X-ray crystallography in the design of antiviral agents. This book focuses on the approach that determines the three-dimensional structures of viruses and virus proteins with biological activity, such as computer molecular modeling. The three-dimensional structures of a number of immune complexes that involve complexes of antigen with antibodies or peptide antigens complexed with an MHC molecule are also deliberated. This text emphasizes that the three-dimensional structures allow the rational design of virus replication inhibitors that control virus infections in man and economically important domestic animals. This publication is a good reference for pharmacists, biochemists, and clinicians researching on the design of antiviral agents.Brunger, A. T. (1988). X-PLOR Manual, Version 1.5, Yale University, New Haven, Connecticut. ... In a€œBiological Organization: Macromolecular Interactions at High Resolutiona€ (R. Burnett, ed.), pp. 125a€”133. Academic ... 10541a€”10544. Dyson, H. J., Cross, K., Houghten, R., Wilson, I. A., Wright, P. E., and Lerner, R. A. (1985).


Title:Use of X-Ray Crystallography in the Design of Antiviral Agents
Author: W Laver
Publisher:Elsevier - 2012-12-02
ISBN-13:

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